VDAC3 Polyclonal Antibody

Product Specifications

Background

Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.

Synonyms

HVDAC3; mVDAC3; Porin, Outer mitochondrial membrane protein porin 3; voltage dependent anion channel 3.

Gene ID

7419

Swiss Prot

Q9Y277

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

101-200/283

Target

VDAC3

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human VDAC3

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

7419

Predicted Cross Reactivity

Human, Dog, Cow, Sheep, Pig, Horse, Rabbit

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS023933-01 48 Well

Horse Complement Factor H ELISA Kit

Ask

View Details

MBS023933-02 96 Well

Horse Complement Factor H ELISA Kit

Ask

View Details

MBS023933-03 5x 96 Well

Horse Complement Factor H ELISA Kit

Ask

View Details

MBS023933-04 10x 96 Well

Horse Complement Factor H ELISA Kit

Ask

View Details

RR207181 10 µg

Nrip3 (NM_001108498) Rat Tagged ORF Clone

Ask

View Details

RM-R152023-01 10 mg

Rotigotine Impurity 23

Ask

View Details