ZNF521 Polyclonal Antibody

Product Specifications

Background

Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes.

Synonyms

Early hematopoietic zinc finger; Early hematopoietic zinc finger protein; EHZF; Evi3; LYST-interacting protein 3; MGC142182; Zfp521; Zinc finger protein 521; ZN521_HUMAN; Znf521.

Gene ID

25925

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

851-950/1311

Target

ZNF521

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human EHZF/ZNF521

Applications

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-6978R

Gene ID URL