A1CF Polyclonal Antibody
Product Specifications
Background
Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay.
Synonyms
A1CF; A1CF_HUMAN; ACF; ACF64; ACF65; Apo B RNA editing protein; Apobec 1 complementation factor; Apobec 1 complementation factor ACF ASP; APOBEC 1 stimulating protein; APOBEC1 complementation factor; APOBEC1 stimulating protein; APOBEC1-stimulating protein; APOBEC1CF; ASP; MGC163391; RP11-564C4.2.
Gene ID
29974
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
101-200/594
Target
A1CF
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human A1CF
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
29974
Predicted Cross Reactivity
Human, Cow, Sheep, Pig
Curated Selection
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