SLC45A3 Polyclonal Antibody
Product Specifications
Background
PSA, prostate specific antigen, is the classic indicator for transformed pro-state tissue; however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia. Prostein, also designated Prostate cancer-associated protein 6, is a prostate-specific, 553 amino acid transmembrane protein that is upregulated by androgens. It is considered a marker for prostate cells since it is expressed in all prostatic glandular cells as well as in normal and cancerous prostate tissues. Since it is able to elicit a tumor-directed cytotoxic T cell response, Prostein may be used as a target for the development of PSA- and T cell-based therapeutic strategies for prostate cancer.
Synonyms
IPCA 2; IPCA 8; IPCA6; PCANAP2; PCANAP6; PCANAP8; Prostate cancer associated gene 2; Prostate cancer associated gene 6; Prostate cancer associated gene 8; Prostate cancer associated protein 2; Prostate cancer associated protein 6; Prostate cancer associated protein 8; Prostate cancer-associated protein 6; Prostein; PRST; S45A3_HUMAN; Slc45a3; Solute carrier family 45 member 3.
Gene ID
85414
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Rat
Immunogen
351-450/553
Target
SLC45A3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human PCANAP2
Applications
WB, ELISA
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
85414
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Sheep, Pig
Curated Selection
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