FbpB Polyclonal Antibody

Product Specifications

Background

The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs) . They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha, alpha-trehalose dimycolate (TDM, cord factor) . They catalyze the transfer of a mycoloyl residue from one molecule of alpha, alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM

Synonyms

M.tuberculosis; Antigen 85 complex B;30 kDa extracellular protein; Mycobacterium; Mycolyl transferase 85B; A85B_MYCTU; Antigen 85-B; 30 kDa extracellular protein; 85B; Ag85B; Extracellular alpha-antigen; Fibronectin-binding protein B.

Gene ID

885785, 886132

Swiss Prot

P9WQP1, P9WQP3

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Bacteria

Immunogen

115-154/325

Target

FbpB

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from Mycobacterium tuberculosis Antigen 85 complex B

Applications

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Specificity

This antibody will detect both Mycobacterium tuberculosis Ag85A and Mycobacterium tuberculosis Ag85B

Gene ID URL

885785, 886132

Cross Reactivity Details

Mycobacteriumtuberculosis

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-54367UV 100 µL

Mouse Monoclonal Connexin 32/GJB1 Antibody (M12.13) [DyLight 350]

Ask

View Details

MR212207 10 µg

Dhrs2 (NM_027790) Mouse Tagged ORF Clone

Ask

View Details

NBP1-92567PEP 0.1 mL

UTP11L Recombinant Protein Antigen

Ask

View Details

A16145-10mM-D 10 mM x 1mL in DMSO

Ciclesonide 10mM * 1mL in DMSO

Ask

View Details