MeCP2 Polyclonal Antibody
Product Specifications
Background
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) -containing DNA, with a preference for 5-methylcytosine (5mC) .
Synonyms
Methyl-CpG-binding protein 2, MECP2, MeCp-2 protein
Gene ID
4204
Swiss Prot
P51608
Host
Rabbit
Cross Reactivity
Human
Target
MeCP2
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Polyclonal antibody raised in rabbit against MeCP2 (Methyl-CpG-binding domain protein 2), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein
Applications
WB, ELISA, dot-blot
Purification
Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
Concentration
1.2µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), dot-blot ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
4204
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