WDR5 Polyclonal Antibody

Product Specifications

Background

Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

Synonyms

WD repeat-containing protein 5, WDR5, BMP2-induced 3-kb gene protein, BIG3

Gene ID

11091

Swiss Prot

P61964

Host

Rabbit

Cross Reactivity

Human

Target

WDR5

Clonality

Polyclonal

Conjugation

Unconjugated

Source

Polyclonal antibody raised in rabbit against human WDR5 (WD (tryptophan-aspartate) repeat domain 5), using a recombinant protein

Applications

WB, IF, ChIP-seq

Purification

Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300

Concentration

2µg/µl

Dilution

WB (1:300-5000), IF (), ChIP-seq ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

11091

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