Ski3 Polyclonal Antibody
Product Specifications
Background
Involved in double-strand break (DSB) formation during meiotic recombination through stabilization of SPO11 association with meiotic chromosome and helping SPO11 to recruit other DSB proteins like REC102 and REC104 to meiotic chromosomes. Also component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly (A) . Essential for controlling the propagation of M double-stranded RNA (dsRNA) and thus for preventing virus-induced cytopathology.
Synonyms
Antiviral protein SKI8, SKI8, Superkiller protein 8, REC13
Gene ID
852659
Swiss Prot
Q02793
Host
Rabbit
Cross Reactivity
Human
Target
Ski3
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Polyclonal antibody raised in rabbit against human SKI3, using a recombinant protein
Applications
WB, IF
Purification
Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300
Concentration
3µg/µl
Dilution
WB (1:300-5000), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
852659
Curated Selection
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