PAPD5 Polyclonal Antibody
Product Specifications
Background
Catalytic subunit of a TRAMP-like complex which has a poly (A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo (A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro) . Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.
Synonyms
Non-canonical poly (A) RNA polymerase PAPD5, PAPD5, TRF4-2, TUTase 3, PAP-associated domain-containing protein 5
Gene ID
64282
Swiss Prot
Q8NDF8
Host
Rabbit
Cross Reactivity
Human
Target
PAPD5
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Polyclonal antibody raised in rabbit against human PAPD5 (PAP associated domain containing 5), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein
Applications
WB
Purification
Whole antiserum from rabbit containing 0.05% azide
Concentration
Not Determined
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
64282
Curated Selection
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