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MBD4 Polyclonal Antibody

Product Specifications

Background

Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.

Synonyms

MED1, Methyl-CpG-binding domain protein 4, MBD4, Methyl-CpG-binding endonuclease 1, Methyl-CpG-binding protein MBD4, Mismatch-specific DNA N-glycosylase

Gene ID

8930

Swiss Prot

O95243

Host

Rabbit

Cross Reactivity

Human

Target

MBD4

Clonality

Polyclonal

Conjugation

Unconjugated

Source

Polyclonal antibody raised in rabbit against human MBD4 (Methyl-CpG-binding domain protein 4), using three different KLH-conjugated synthetic peptides

Applications

WB, ELISA

Purification

Whole antiserum from rabbit containing 0.05% azide

Concentration

Not Determined

Dilution

WB (1:300-5000), ELISA (1:500-1000)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

8930

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