POLK Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016]
Synonyms
DINP; POLQ; DINB1; DNA polymerase kappa; DINB protein; POLK_HUMAN.
Gene ID
51426
Swiss Prot
Q9UBT6
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
1-472/870
Target
POLK
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
Recombinant human POLK protein
Applications
IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC-P (1:200-400), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
51426
Predicted Cross Reactivity
Mouse
Curated Selection
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