PLDL1 Polyclonal Antibody

Product Specifications

Background

PLCL1 is involved an inositol phospholipid based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and sphatidylinositol. Component in the dependent endocytosis process of GABA A receptor (By similarity) . Regulates the turnover of receptors and thus contributes to the maintenance of GABA mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.

Synonyms

PLCL1; PLCE; Phospholipase C deleted in lung carcinoma; Phospholipase C epsilon; Phospholipase C like 1; Phospholipase C related but catalytically inactive protein; Phospholipase C related, but catalytically inactive protein; PLCE; PLCL; PRIP; Plcl1; C230017K02Rik; KIAA1092; PLC-L; PLC-L1; PLCE; PLCL; PRIP; PRIP-1; PLCL1_HUMAN.

Gene ID

5334

Cellular Locus

Cytoplasm

Host

Rabbit

Immunogen

1001-1096/1096

Target

PLDL1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human PLCL1

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Specificity

This antibody may exhibit a slight secondary cross-reactivity with PLCL2 due to a 69% non-sequential sequence similarity over the immunogen range.

Gene ID URL

5334

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Pig, Horse

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