CTDSPL Polyclonal Antibody
Product Specifications
Background
Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity) . Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.
Synonyms
PSR1; SCP3; HYA22; RBSP3; C3orf8; CTD small phosphatase-like protein; CTDSP-like; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; NIF-like protein; Nuclear LIM interactor-interacting factor 1; NLI-interacting factor 1; Protein YA22; Small C-terminal domain phosphatase 3; Small CTD phosphatase 3; CTDSPL; NIF1; NIFL; YA22
Gene ID
10217
Swiss Prot
O15194
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
145-250/276
Target
CTDSPL
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human CTDSPL
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
10217
Predicted Cross Reactivity
Dog, Cow, Pig, Chicken, Rabbit
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1471176-01 0.02 mg (E-Coli)
Recombinant Pseudomonas syringae pv. tomato Adenylosuccinate synthetase (purA)
Ask
View Details MBS1471176-02 0.02 mg (Yeast)
Recombinant Pseudomonas syringae pv. tomato Adenylosuccinate synthetase (purA)
Ask
View Details 
MBS1471176-03 0.1 mg (E-Coli)
Recombinant Pseudomonas syringae pv. tomato Adenylosuccinate synthetase (purA)
Ask
View Details