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Glypican 1 Polyclonal Antibody, HRP Conjugated

Product Specifications

Background

Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity) . May act as a catalyst in increasing the rate of conversion of prion protein PRPN (C) to PRNP (Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

Synonyms

Glypican; Glypican-1; GPC1

Gene ID

2817

Swiss Prot

P35052

Cellular Locus

Cytoplasm, Secreted, Cell membrane, Extracellular matrix

Host

Rabbit

Immunogen

301-400/558

Target

Glypican 1

Clonality

Polyclonal

Isotype

IgG

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human glypican 1

Applications

ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-2426R-HRP

Gene ID URL

2817

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Horse

Curated Selection

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