SENP2 Polyclonal Antibody, Cy5 Conjugated

Product Specifications

Background

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620) .

Synonyms

AXAM2; SMT3IP2; Sentrin-specific protease 2; SMT3-specific isopeptidase 2; Sentrin/SUMO-specific protease SENP2; SENP2; KIAA1331

Gene ID

59343

Swiss Prot

Q9HC62

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

1-100/589

Target

SENP2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human SENP2

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

59343

Predicted Cross Reactivity

Human, Rat

Curated Selection

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