E2F3 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity) .
Synonyms
E2F-3; Transcription factor E2F3; E2F3; KIAA0075
Gene ID
1871
Swiss Prot
O00716
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
381-465/465
Target
E2F3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human E2F3
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
1871
Predicted Cross Reactivity
Human, Rat, Dog, Cow, Pig, Horse, Rabbit
Available Sizes
Curated Selection
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