PDCD4 Polyclonal Antibody

Product Specifications

Background

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity) .

Synonyms

H731; Programmed cell death protein 4; Neoplastic transformation inhibitor protein; Nuclear antigen H731-like; Protein 197/15a; PDCD4

Gene ID

27250

Swiss Prot

Q53EL6

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

1-100/469

Target

PDCD4

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human PDCD4

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

27250

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

FAB12571L 0.1 mL

Mouse Monoclonal Fc gamma RI/CD64 Antibody (276426) [DyLight 550]

Ask

View Details

NBP2-90096AF647 0.1 mL

Rabbit Monoclonal CD58/LFA-3 Antibody (085) [Alexa Fluor 647]

Ask

View Details

NBP2-90507JF646 0.1 mL

Rabbit Monoclonal Dectin-2/CLEC6A Antibody (003) [Janelia Fluor 646]

Ask

View Details

E3352-01-ML550 100 µL

Eotaxin 3 (MaxLight 550) discontinued

Ask

View Details

MBS1463405-01 0.02 mg (E-Coli)

Recombinant Giardia lamblia virus Major capsid protein (gag), partial

Ask

View Details

MBS1463405-02 0.1 mg (E-Coli)

Recombinant Giardia lamblia virus Major capsid protein (gag), partial

Ask

View Details