Prednicarbate

Prednicarbate is a topical corticosteroid agent. Prednicarbate can be used for the research of inflammatory skin diseases, such as atopic dermatitis[1][2].

Product Specifications

CAS Number

[73771-04-7]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Glucocorticoid Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/prednicarbate.html

Concentration

10mM

Purity

99.81

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

CCC(OCC([C@@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@@]4(C(CC3)=CC(C=C4)=O)C)([H])[C@H](C2)O)([H])CC1)C)OC(OCC)=O)=O)=O

Molecular Formula

C27H36O8

Molecular Weight

488.57

Precautions

H302, H315, H319, H335

References & Citations

[1]Lubach D, et, al. Investigation of the skin thinning effect of prednicarbate and other corticoids in mouse skin. Skin Pharmacol. 1988;1 (3) :200-6.|[2]Lee KH, et, al. Hizikia fusiformis fractions successfully improve atopic dermatitis indices in anti-CD3-stimulated splenocytes and 2,4-dinitrochlorobenzene-treated BALB/c mice. J Pharm Pharmacol. 2014 Mar;66 (3) :466-76.