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EXOC3L2 Polyclonal Antibody

Product Specifications

Background

Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. The exocyst complex inhibits tubulin polymerization in vitro, suggesting that the exocyst complex is important for modulating the microtubule dynamics that underlie exocytosis. ExoC3L2 (Exocyst complex component 3-like protein 2), also known as HBV X-transactivated gene 7 protein, is a 409 amino acid protein that is related to the Sec6 component of the exocyst complex.

Synonyms

Exocyst complex component 3 like; Exocyst complex component 3 like protein 2; FLJ36147; EX3L2_HUMAN; HBV X transactivated gene 7 protein; HBV XAg transactivated protein 7; MGC16332; OTTHUMP00000207128; OTTMUSP00000045827; Protein 7 transactivated by hepatitis B virus X antigen (HBxAg) ; XTP7.

Gene ID

90332

Swiss Prot

Q2M3D2

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

151-250/409

Target

EXOC3L2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human EXOC3L2

Applications

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

90332

Predicted Cross Reactivity

Human, Mouse, Cow

Curated Selection

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