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CLEC9A Polyclonal Antibody

Product Specifications

Background

The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-9A (C-type lectin domain family 9 member A), also known as DNGR1 (dendritic cell natural killer lectin group receptor 1), is a 241 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Expressed in myeloid lineage cells, brain, spleen and thymus, CLEC-9A is a group V C-type lectin-like receptor (CTLR) that acts as an activation receptor. The gene encoding CLEC-9A maps to human chromosome 12p13.2 and mouse chromosome 6 F3.

Synonyms

C type lectin domain family 9, member A; C-type lectin domain family 9 member A; CLC9A_HUMAN; CLEC9A; DNGR1; HEEE9341; PRO34046; UNQ9341.

Gene ID

232414

Swiss Prot

Q8BRU4

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

1-100/238

Target

CLEC9A

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from mouse CLEC9A

Applications

WB, ELISA, IHC-P, IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

232414

Predicted Cross Reactivity

Rat

Curated Selection

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