DAP5 Polyclonal Antibody
Product Specifications
Background
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G) . Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
Synonyms
Death Associated Protein-5; Death associated protein 5; Eukaryotic translation initiation factor 4 gamma 2; Nat1; Novel APOBEC-1 target 1; Translation repressor NAT1.
Gene ID
1982
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Rat
Immunogen
41-150/907
Target
DAP5
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human DAP-5
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
1982
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit, GuineaPig
Curated Selection
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