GBA2 Polyclonal Antibody

Product Specifications

Background

Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.

Synonyms

AD035; SPG46; NLGase; Non-lysosomal glucosylceramidase; Beta-glucocerebrosidase 2; Beta-glucosidase 2; Glucosylceramidase 2; GBA2; KIAA1605

Gene ID

57704

Swiss Prot

Q9HCG7

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

601-700/927

Target

GBA2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human GBA2

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

57704

Predicted Cross Reactivity

Rat, Dog, Cow, Sheep, Pig, Chicken

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