PLCD1/NDNC3 Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3) . The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Synonyms
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta 1; NDNC3; Phosphoinositide phospholipase C; Phosphoinositide phospholipase C delta 1; Phospholipase C delta 1; Phospholipase C III; PLC delta 1; PLC III. PLCD1_HUMAN
Gene ID
5333
Swiss Prot
P51178
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
211-310/756
Target
PLCD1/NDNC3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human PLCD1/NDNC3
Applications
IHC-P, IHC-F, IF (ICC), IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC-P (1:200-400), IHC-F (1:100-500), IF (ICC) (1:50-200), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
5333
Predicted Cross Reactivity
Human, Cow, Sheep, Pig, Horse, Rabbit, GuineaPig
Curated Selection
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