VAC14 Polyclonal Antibody
Product Specifications
Background
The content of phosphatidylinositol 3,5-bisphosphate (PtdIns (3,5) P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns (3,5) P2. Other components of this complex are the PtdIns (3,5) P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns (3,5) P2 phosphatase FIG4 (MIM 609390) . VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]) .[supplied by OMIM, Feb 2010]
Synonyms
ArPIKfyve; FLJ10305; FLJ36622; FLJ46582; MGC149815; MGC149816; OTTHUMP00000174908; Protein VAC14 homolog; Tax1 (human T cell leukemia virus type I) binding protein 1; Tax1 (human T cell leukemia virus type I) binding protein 2; Tax1 binding protein 2; Tax1-binding protein 2; TAX1BP2; TRX; VAC 14; vac14; Vac14 homolog (S. cerevisiae) ; Vac14 homolog; VAC14_HUMAN.
Gene ID
55697
Swiss Prot
Q08AM6
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
1-50/782
Target
VAC14
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human VAC14
Applications
IHC-P, IHC-F, IF (ICC), IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC-P (1:200-400), IHC-F (1:100-500), IF (ICC) (1:50-200), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
55697
Predicted Cross Reactivity
Human, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit, Zebrafish
Curated Selection
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