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SLC35C2 Polyclonal Antibody

Product Specifications

Background

SLC35C2 (solute carrier family 35, member C2), also known as C20orf5, OVCOV1 or CGI-15, is a 365 amino acid multi-pass membrane protein that belongs to the TPT transporter family and exists as multiple alternatively spliced isoforms. Expressed ubiquitously and functionally induced in hypoxic trophoblast cells, SLC35C2 plays a role in the cellular response to tissue hypoxia and is thought to be involved in the pathogenesis of ovarian cancer. The gene encoding SLC35C2 maps to human chromosome 20, which houses over 600 genes some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

Synonyms

BA394O2.1; C20orf5; CGI-15; FLJ37039; MGC20633; MGC32079; MGC39183; Ovarian cancer-overexpressed gene 1 protein; OVCOV1; S35C2_HUMAN; SLC35C2; Solute carrier family 35 member C2.

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

81-200/365

Target

SLC35C2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human SLC35C2

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Predicted Cross Reactivity

Cow, Sheep, Pig, Horse, Chicken, Rabbit

Curated Selection

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