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TWSG1 Polyclonal Antibody

Product Specifications

Background

Twisted Gastrulation Protein 1 (TWSG1) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins thereby preventing BMPs from binding to their receptors. It can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex.

Synonyms

PSEC0250; TSG; TSG1; twisted gastrulation homolog 1; Twisted gastrulation protein; TWSG1_HUMAN.

Cellular Locus

Secreted

Host

Rabbit

Immunogen

151-223/223

Target

TWSG1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human TWSG1

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Sheep, Pig

Curated Selection

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