ERC2 Polyclonal Antibody

Product Specifications

Background

ERCs (ERC1 and ERC2) also referred to as ELKS and CAST are related proteins which share an identical C-terminal sequence. They interact with the conserved RIM PDZ domain via an unusual PDZ binding motif. ERC2/CAST 1 is only expressed as a single RIM binding variant. All ERCs have been shown to interact with Rab6, a protein involved in membrane trafficking at the Golgi complex. The function of these proteins has not been determined yet. They may link Rab6 mediated non-neuronal membrane traffic at the Golgi complex to neuronal membrane traffic at the active zone executed via RIMs.

Synonyms

Cast; CAST1; CAZ-associated structural protein 1; Cmbp gene name; Cytomatrix protein p110; ERC protein 2; KIAA0378; ERC2_HUMAN.

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Immunogen

361-460/957

Target

ERC2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human CAST1

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

GTR15269387 1 Vial

Lentiviral mouse Actb shRNA (UAS) - Lentiviral mouse Actb shRNA (UAS, RFP) (25)

Ask

View Details

MBS9330548-01 48 Well

Mouse Lipid phosphate phosphohydrolase 2, PPAP2C ELISA Kit

Ask

View Details

MBS9330548-02 96 Well

Mouse Lipid phosphate phosphohydrolase 2, PPAP2C ELISA Kit

Ask

View Details

MBS9330548-03 5x 96 Well

Mouse Lipid phosphate phosphohydrolase 2, PPAP2C ELISA Kit

Ask

View Details

MBS9330548-04 10x 96 Well

Mouse Lipid phosphate phosphohydrolase 2, PPAP2C ELISA Kit

Ask

View Details

GTR15128713 1 Vial

Lentiviral human COX8A shRNA (UAS) - Lentiviral human COX8A shRNA (UAS, RFP) plasmid

Ask

View Details