NCoR1 Polyclonal Antibody
Product Specifications
Background
Nuclear co-repressor 2 (N-CoR2) gene (NCOR2, previously called silencing mediator for retinoid and thyroid hormone receptor SMRT) is recruited to nuclear and non-nuclear receptors in a large repressing complex containing also N-CoR1, mSin3 and HDACs. This large complex represses transcription in absence of ligand. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Tissue specificity: Ubiquitous. It is belongs to the N-CoR nuclear receptor corepressors family.
Synonyms
RIP13; Rxrip13; hCIT529I10; hN CoR; hNCoR; KIAA1047; MGC104216; N CoR; N Cor/SMRT corepressor Rip13; N CoR1; NCOR 1; NCoR; NCOR1; Nuclear receptor co repressor 1; Nuclear receptor corepressor 1; Retinoid X receptor interacting protein 13; thyroid hormone and retinoic acid receptor associated corepressor 1; thyroid hormone- and retinoic acid receptor-associated corepressor 1; TRAC 1; TRAC1; Nuclear Receptor Corepressor NCoR; NCOR1_MOUSE.
Gene ID
9611
Cellular Locus
Nucleus
Host
Rabbit
Immunogen
2301-2400/2453
Target
NCoR1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human NC0R1
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
9611
Predicted Cross Reactivity
Human, Mouse, Rat
Curated Selection
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