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CD207 Recombinant Antibody

Product Specifications

Background

Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs) ; is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur.

Synonyms

CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CLEC4K; Langerhans cell specific c type lectin; Langerin.

Gene ID

50489

Swiss Prot

Q9UJ71

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

CD207

Clonality

Recombinant

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human CD207

Applications

IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

IHC-P (1:200-400), IHC-F (1:100-500), IF ()

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

50489

Isotype

IgG

Curated Selection

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