Alas1 (1G11) Recombinant Antibody
Product Specifications
Background
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Synonyms
5-aminolevulinate synthase, nonspecific, mitochondrial; ALAS1; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1; ALAS1; ALAS3; ALASH; OK/SW-cl.121
Gene ID
211
Swiss Prot
P13196
Host
Rabbit
Cross Reactivity
Human
Target
Alas1 (1G11)
Clonality
Recombinant
Conjugation
Unconjugated
Source
Recombinant human Alas1 protein, around C-terminal 200aa.
Applications
WB
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
211
Isotype
IgG
Curated Selection
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