CDCA2 Polyclonal Antibody

Product Specifications

Background

Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.

Synonyms

PPP1R81; Repo-Man; Cell division cycle-associated protein 2; Recruits PP1 onto mitotic chromatin at anaphase protein; CDCA2

Gene ID

157313

Swiss Prot

Q69YH5

Cellular Locus

Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

361-450/1023

Target

CDCA2

Clonality

Polyclonal

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human CDCA2

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Prediction Reactivity

Rat, Dog, Pig, Horse, Rabbit

Gene ID URL

157313

Isotype

IgG

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