MDMX Polyclonal Antibody

Product Specifications

Background

Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Synonyms

HDMX; MDMX; MRP1; Protein Mdm4; Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4; MDM4

Gene ID

4194

Swiss Prot

O15151

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

301-400/490

Target

MDMX

Clonality

Polyclonal

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human MDM4

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Prediction Reactivity

Human, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit

Gene ID URL

4194

Isotype

IgG

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

GTR15423475 1 Vial

Mino/GFP stable cell line

Ask

View Details

NBP1-97676F 0.1 mL

Mouse Monoclonal Cadherin-11 Antibody (16A) [FITC]

Ask

View Details

145806 50 µg

Integrin alpha 10 beta 1, Recombinant, Mouse, aa23-1119

Ask

View Details

RR200789L4 10 µg

S1pr2 (NM_017192) Rat Tagged Lenti ORF Clone

Ask

View Details

GTR15409788 1 Vial

Human MON1A Knockout A549 cell line

Ask

View Details