TLR7 Polyclonal Antibody
Product Specifications
Background
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity) .
Synonyms
TLR7-like; Toll-like receptor 7; TLR7; UNQ248/PRO285
Gene ID
51284
Swiss Prot
Q9NYK1
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
461-560/1049
Target
TLR7
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human TLR7
Applications
WB, ELISA
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (WB=1:500-2000), ELISA (ELISA=1:5000-10000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
51284
Isotype
IgG
Curated Selection
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