Phospho-Bcl-2 (Ser70) Polyclonal Antibody
Product Specifications
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) .
Synonyms
Bcl-2; Apoptosis regulator Bcl-2; Bcl2
Gene ID
24224
Swiss Prot
P49950
Modification Site
Ser70
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-Bcl-2 (Ser70)
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic phosphopeptide derived from rat Bcl-2 around the phosphorylation site of Ser70
Applications
WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Product Datasheet
https://www.biossantibodies.com/datasheets/bs-3052R
Prediction Reactivity
Mouse, Rat, Dog, Rabbit
Gene ID URL
24224
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse HMWK Matched Antibody Pair Set [ABP-S-04487]](https://cdn.genprice.uk/genprice/genprice5.png)
MBS9935132 Inquire
Duck Transcription Initiation Factor IIE Subunit Beta (GTF2E2) ELISA Kit
Ask
View Details 