DKK3 Polyclonal Antibody
Product Specifications
Background
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity) .
Synonyms
RIG; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3; DKK3; UNQ258/PRO295
Gene ID
27122
Swiss Prot
Q9UBP4
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
31-130/350
Target
DKK3
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human DKK3
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Human, Rat, Cow, Pig, Horse, Rabbit
Gene ID URL
27122
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal PDGFRL Antibody (1008804) [CoraFluor 1]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)