PDE5A Polyclonal Antibody
Product Specifications
Background
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:9714779, PubMed:15489334) . Specifically regulates nitric-oxide-generated cGMP (PubMed:15489334) .
Synonyms
CN5A; PDE5; CGB-PDE; cGMP-specific 3',5'-cyclic phosphodiesterase; cGMP-binding cGMP-specific phosphodiesterase; PDE5A
Gene ID
8654
Swiss Prot
O76074
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
101-200/875
Target
PDE5A
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human PDE5A
Applications
WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit, GuineaPig
Gene ID URL
8654
Isotype
IgG
Curated Selection
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