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IL-11 Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production.Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.

Synonyms

Interleukin-11; Adipogenesis inhibitory factor; AG; IL 11; IL11; Interleukin 11; Oprelvekin; IL11_HUMAN.

Gene ID

3589

Swiss Prot

P20809

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

22-120/199

Target

IL-11

Clonality

Polyclonal

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human IL-11

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-1827R-Cy3

Prediction Reactivity

Dog, Cow, Pig, GuineaPig

Gene ID URL

3589

Isotype

IgG

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