GLK Polyclonal Antibody
Product Specifications
Background
Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
Synonyms
GK; GLK; HK4; HHF3; HKIV; HXKP; LGLK; MODY2; FGQTL3; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-4; Hexokinase-D; GCK
Gene ID
2645
Swiss Prot
P35557
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
101-200/465
Target
GLK
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human GCK
Applications
WB, ELISA, FCM, IHC-P
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse, Dog, Pig, Horse, Chicken, Rabbit
Gene ID URL
2645
Isotype
IgG
Curated Selection
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