Phospho-CDK7 (Thr170) Polyclonal Antibody, PE-Cy5 Conjugated
Product Specifications
Background
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK) . It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Synonyms
CDK7 (phospho Thr170) ; CDK7 (phospho T170) ; Cyclin H; MAT1; Cyclin Dependent Kinase 7; CAK1; MO15; CDKN7; serine/threonine kinase; STK1; serine/threonine protein kinase 1; MO15 homolog, Xenopus laevis, cdk-activating kinase; Cdk-activating kinase; serine/threonine protein kinase MO15; homolog of Xenopus MO15 Cdk-activating kinase; kinase subunit of CAK; 39 KDa protein kinase; CR4 protein kinase; CRK4; CDK7_HUMAN.
Gene ID
1022
Swiss Prot
P50613
Modification Site
Thr170
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-CDK7 (Thr170)
Clonality
Polyclonal
Conjugation
PE-Cy5
Source
KLH conjugated Synthesised phosphopeptide derived from human CDK7 around the phosphorylation site of Thr170
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
1ug/ul
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.biossantibodies.com/datasheets/bs-10997R-PE-Cy5
Prediction Reactivity
Mouse, Rat, Dog, Pig, Horse, Rabbit
Gene ID URL
1022
Isotype
IgG
Curated Selection
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