BGG463
Product Specifications
UNSPSC Description
BGG463 (K03859) is an orally active type II CDK2 inhibitor[1].
Target Antigen
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/BGG463.html
Purity
98.0
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C(C1=C2C=CC(OC3=NC=NC(NC(C)=O)=C3)=CC2=CC=C1)NC4=CC=C(CN5CCN(C)CC5)C(C(F)(F)F)=C4
Molecular Weight
578.58
References & Citations
[1]Alexander LT, et al. Type II Inhibitors Targeting CDK2. ACS Chem Biol. 2015 Sep 18;10(9):2116-25.|[2]Jones K, et al. Cancer Drug Discovery 2010: from molecules to medicine. Expert Rev Clin Pharmacol. 2010 Sep;3(5):613-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100600/BGG463-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100600/BGG463-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
890129-26-7
Available Sizes
Curated Selection
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