BGG463
BGG463 (K03859) is an orally active type II CDK2 inhibitor[1].
Product Specifications
CAS Number
[890129-26-7]
Product Name Alternative
K03859
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/BGG463.html
Purity
98.0
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C(C1=C2C=CC(OC3=NC=NC(NC(C)=O)=C3)=CC2=CC=C1)NC4=CC=C(CN5CCN(C)CC5)C(C(F)(F)F)=C4
Molecular Formula
C30H29F3N6O3
Molecular Weight
578.58
References & Citations
[1]Alexander LT, et al. Type II Inhibitors Targeting CDK2. ACS Chem Biol. 2015 Sep 18;10 (9) :2116-25.|[2]Jones K, et al. Cancer Drug Discovery 2010: from molecules to medicine. Expert Rev Clin Pharmacol. 2010 Sep;3 (5) :613-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2
Available Sizes
Curated Selection
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