RPSA Polyclonal Antibody

Product Specifications

Background

Required for the assembly and/or stability of the 4S ribosomal subunit. Required for the processing of the 2S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 4S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.

Synonyms

SA; LBP; LRP; p4; 67LR; ICAS; lamR; 37LRP; LAMBR; LAMR1; LRP/LR; LBP/p4; NEM/1CHD4; 4S ribosomal protein SA; 37 kDa laminin receptor precursor; 37/67 kDa laminin receptor; 67 kDa laminin receptor; Colon carcinoma laminin-binding protein; Laminin receptor 1; Laminin-binding protein precursor p4; Multidrug resistance-associated protein MGr1-Ag; RPSA

Gene ID

3921

Swiss Prot

P08865

Cellular Locus

Cytoplasm, Nucleus, Cell membrane, Extracellular matrix

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

201-295/295

Target

RPSA

Clonality

Polyclonal

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human LAMR1

Applications

WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)