CIAP1 Ligand-Linker Conjugates 6 (hydrochloride)
CIAP1 Ligand-Linker Conjugates 6 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 6 hydrochloride can be used to design SNIPERs[1].
Product Specifications
Product Name Alternative
E3 ligase Ligand-Linker Conjugates 35 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugates-35-hydrochlride.html
Solubility
10 mM in DMSO
Smiles
CC(C)C[C@H](NC([C@H]([C@@H](CC1=CC=CC=C1)NC(OCC2C3=C(C=CC=C3)C4=C2C=CC=C4)=O)O)=O)C(OCCOCCOCCOCCN)=O.Cl
Molecular Formula
C39H52ClN3O9
Molecular Weight
742.30
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19 (22) :6768-78.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128814/cIAP1-Ligand-Linker-Conjugates-6-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128814/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CIAP1
Available Sizes
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