AMPK beta 2
Product Specifications
Background
AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase. This is a regulatory subunit, may be a positive regulator of AMPK activity. It may also serve as an adapter molecule for the catalytic alpha-subunit.
Synonyms
AMP activated protein kinase beta 2 non catalytic subunit; AMPK beta 2; AMPK beta 2 chain; PRKAB 2; Protein kinase AMP activated beta 2 non catalytic subunit; AAKB2_HUMAN; AMPK b2; AMPK-b2.
Gene ID
5565
Swiss Prot
O43741
Cellular Locus
Cytoplasm, Nucleus
Host
Mouse
Cross Reactivity
Mouse, Rat
Target
PRKAB2
Clonality
Monoclonal
Isotype
IgG
Conjugation
Unconjugated
Source
Recombinant human AMPK beta 2
Applications
WB, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
1mg/ml
Dilution
WB (WB=1:1000-2000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:400-800), IF (IF=1:100-500)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
5565
Predicted Cross Reactivity
Human
Curated Selection
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