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CRIPTO (2B11) Monoclonal Antibody

Product Specifications

Background

This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].

Synonyms

CRIPTO; CRIPT; CR; CRGF; Cripto 1; Cripto-1; Cripto 1 growth factor; Cripto-1 growth factor; Cripto1; Cripto1 growth factor; Epidermal growth factor like cripto protein CR1; Epidermal growth factor-like cripto protein CR1; TDGF 1; TDGF-1; TDGF1; Teratocarcinoma derived growth factor 1; Teratocarcinoma-derived growth factor 1; teratocarcinoma-derived growth factor 1 isoform 1 precursor; TDGF1_HUMAN.

Gene ID

6997

Host

Mouse

Cross Reactivity

Human, Rat

Immunogen

101-188/188

Target

CRIPTO

Clonality

Monoclonal

Isotype

IgG

Clone

2B11

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human Teratocarcinoma-derived growth factor 1

Applications

WB, ELISA, ICC/IF

Purification

Purified by Protein G.

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000), ELISA (ELISA=1:5000-10000), ICC/IF (ICC/IF=1:100-500)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

6997

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