7alpha-Hydroxycholesterol
Product Specifications
Background
Metabolite resulting from the action of cholesterol 7 alpha-hydroxylase on cholesterol. 7α-Hydroxycholesterol is the first intermediate and a rate-limiting step in the major pathway for bile acid synthesis in humans. A pro-inflammatory mediator which upregulates production of CCL2 and MMP9 in macrophages and may promote progression of atherosclerosis.2,3 Possible biomarker for cellular lipid peroxidation.4
Conjugation
Unconjugated
Buffer
White or pale yellow solid
Storage Conditions
-20°C
Available Sizes
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