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SP-600125

Product Specifications

Background

Selective inhibitor of c-Jun N-terminal kinase (JNK) . Reversibly inhibits JNK1,2 and 3 (IC50’s range from 40-90 nM) . >300-fold selectivity for JNK as compared to related MAP kinases. Antiinflammatory activity. Inhibits expression of presenilin-1 and Notch signaling in mouse brain. Cell permeable and active in vivo.

Conjugation

Unconjugated

Buffer

Yellow solid

Storage Conditions

RT

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-82020C

Available Sizes

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