CDC25C Antibody

This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq].

Product Specifications

Specifications

Western blot: 1:1000-1:8000

UniProt

P30307

Host

Mouse

Reactivity

Human

Immunogen

This CDC25C antibody was produced from mouse immunized with CDC25C recombinant protein.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

233CT9.6.6

Applications

WB, ELISA

Purity

Ascites

Format

Ascites

Limitations

This CDC25C antibody is available for research use only.

Storage Conditions

Aliquot the CDC25C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In ascites with 0.09% sodium azide

Applications Notes

Titration of the CDC25C antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of CDC25C antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2) with the CDC25C gene. Expected molecular weight: ~53/60 kDa (unmodified/phosphorylated) .