RAB3GAP2 Antibody

Rab3 GTPase-activating protein non-catalytic subunit is an enzyme that in humans is encoded by the RAB3GAP2 gene. It is mapped to 1q41. The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.

Product Specifications

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q9H2M9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids M1-Q115 from the human protein were used as the immunogen for the RAB3GAP2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, FACS, Direct ELISA

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Limitations

This RAB3GAP2 antibody is available for research use only.

Storage Conditions

Store the RAB3GAP2 antibody at -20°C.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the RAB3GAP2 antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) K562, 2) HL60, 3) ThP-1, 4) Raji, 5) HeLa and 6) HepG2 cell lysate with RAB3GAP2 antibody. Predicted molecular weight ~156 kDa.