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Anti-TAZ Antibody

Our TAZ rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat TAZ and is antigen affinity purified. It is great for use in WB.

Product Specifications

Background

Highly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation, cell cycle progression and apoptosis by binding intracellular phosphoproteins involved in signal transduction. A novel transcriptional co-activator, TAZ (transcriptional co-activator with PDZ-binding motif) functions as a 14-3-3-binding molecule. TAZ may link events at the plasma membrane and cytoskeleton to nuclear transcription in a manner that can be regulated by 14-3-3.

Synonyms

Barth syndrome, tafazzin, Cardiomyopathy dilated 3A (X linked), BTHS, CMD3A, EFE, LVNCX, G4.5

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

TAFAZZIN

UniProt

Q16635

Host

Rabbit

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide corresponding to amino acids from the PDZ-binding domain of human TAZ protein

Immunogen Type

Human

Target

TAZ

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Molecular Weight

49

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

WB Dilution

1:500-1:1000

Specificity

Reacts with the PDZ-binding domain of the 49 kDa human, mouse and rat TAZ protein.

Formulation

Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.

Quality Control

Western blots performed on each lot.

Isotype

IgG

Curated Selection

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